Evaluation of Intra-Detrusor Injection of Botulinum A Toxin in Neurogenic Bladder in Patients with Multiple Sclerosis
ASHRAF GAMAL FAHMY;
Abstract
Abstract
Background: Early diagnosis and amelioration of lower urinary tract symptoms is a key
focus in the management of multiple sclerosis. Untreated LUTS can lead to increased
morbidity and mortality, for instance as a result of irreversible changes in the lower
urinary tract itself, recurrent UTIs, renal stones, renal function impairment, and lowered
HR-QoL. Aim of the Work: to assess the effects of intradetrusor muscle injection of
botulinum A toxin on urgency & urgency urinary incontinence, urodynamic variables, and
quality of life in patients with MS and voiding dysfunction. Patients and Methods: This
prospective randomized control study was conducted on 40 patients recruited after signing
a formal consent. The patients had been subjected to cystoscopy and intradetrusor
injection of 200 U of botulinum A toxin, sparing the trigon, with consent to do CIC if
needed. We had compared between the results of urodynamics and patients’ satisfaction
before and after botulinum A toxin injection. :
Background: Early diagnosis and amelioration of lower urinary tract symptoms is a key
focus in the management of multiple sclerosis. Untreated LUTS can lead to increased
morbidity and mortality, for instance as a result of irreversible changes in the lower
urinary tract itself, recurrent UTIs, renal stones, renal function impairment, and lowered
HR-QoL. Aim of the Work: to assess the effects of intradetrusor muscle injection of
botulinum A toxin on urgency & urgency urinary incontinence, urodynamic variables, and
quality of life in patients with MS and voiding dysfunction. Patients and Methods: This
prospective randomized control study was conducted on 40 patients recruited after signing
a formal consent. The patients had been subjected to cystoscopy and intradetrusor
injection of 200 U of botulinum A toxin, sparing the trigon, with consent to do CIC if
needed. We had compared between the results of urodynamics and patients’ satisfaction
before and after botulinum A toxin injection. :
Other data
| Title | Evaluation of Intra-Detrusor Injection of Botulinum A Toxin in Neurogenic Bladder in Patients with Multiple Sclerosis | Other Titles | تقييم حقن سم البتيولينم في جدار المثانة لعلاج المثانة العصبية لدى مرضى التصلب المتعدد | Authors | ASHRAF GAMAL FAHMY | Issue Date | 2019 |
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