Titrated oral misoprostol solution versus vaginal misoprostol for labor induction in primi gravid ladies

Abstract

At present, agents specifically approved by US Food and Drug Administration (FDA) for labor induction is dinoprostone and misoprostol. Misoprostol; a PGE1 analog has been shown to be an efficacious agent of cervical ripening and labor induction, available as tablet or suppository, and it is inexpensive, not requires refrigeration and mostly does not need oxytocin augmentation. In this study, we aimed to compare safety and efficacy of titrated oral misoprostol compared to vaginal misoprostol for labor induction.