The Efficacy of Intravenous Tranexamic Acid in Reduction of Blood Loss In Women At High Risk of Postpartum Hemorrhage

Abstract

The underwent study is a double blinded, randomized, controlled trial that was carried out on 200 women attending the labor ward in Ain Shams University Maternity hospital for delivery by cesarean section or vaginal delivery who were ar risk of PPH . One hundred women received 1 gm tranexamic acid in addition to oxytocin after delivery of the baby; the other 100 women received oxytocin only. The women were monitored for the occurrence of postpartum hemorrhage in the form of intra-operative blood loss, intra-operative or post-operative need for surgical measures to stop bleeding, post-operative vaginal bleeding, also drop in hemoglobin and hematocrit 24 hours postoperative beside the need for blood transfusion.