Vitamin D Deficiency among Women with Unexplained Infertility

Abstract

Infertility is a disease, defined by the failure to achieve a successful pregnancy after 12 months or more of appropriate, timed unprotected intercourse or therapeutic donor insemination. Earlier evaluation and treatment may be justified based on medical history and physical findings and is warranted after 6 months for women over age 35 years. The causes of female infertility are different and include genetic and anatomic abnormalities as well as endocrine and autoimmune disorders (ADs). Once infertility has been ascertained, regardless of which definition one uses, the (diagnosis) of unexplained female infertility is made when tubal patency and normal ovulatory function are established in the presence of A normal semen analysis. Vitamin D is a steroid hormone well known for its role in calcium homeostasis and bone mineralization. It is mainly produced in the skin after sunlight exposure. Diet and dietary supplements constitute alternative sources of vitamin D for humans. There are two distinct forms of vitamin D, that of D2 or ergocalciferol and D3 or