Role of Neoadjuvant Chemotherapy in Cases of Gastric Cancer

Abstract

his study favors the idea of Neoadjuvant chemotherapy usage prior to any surgical intervention in early stage gastric cancer. However, there were other studies that questions its role and demand a reconsideration about the oncological and clinical outcome which require further investigation. In conclusion, the role of chemotherapy is continuing to solidify in the neoadjuvant and adjuvant settings for patients with stomach cancer. Recent large phase III studies have shown that multi-modality therapy including surgery provide statistically signifi-cant improved survival for locally advanced disease when compared to surgery alone. In the future, larger randomized controlled studies, perhaps focused only on neoadjuvant chemotherapy, may demonstrate further improved patient outcomes with improved treatment tolerability and reduced morbidity. T