Propranolol and Oxytocin versus Oxytocin Alone for Induction of Labor: A Randomized Controlled Trial

Abstract

Labor is a state of uterine contractions having adequate frequency, duration, and strength resulting in cervical effacement and dilatation .Prolonged labor could cause maternal and neonatal medical issues and these unfavorable labor clinical outcomes are elevated in prolonged gestations in comparison with term pregnancies. The cesarean section rates are rising during the last decades according to international research data. Prior research studies have revealed and displayed that labor induction could be correlated with raised Cesarean section rates. Numerous agents are implemented for labor induction and augmentation prostaglandins and oxytocin are the most widely used agents in practice . Intravaginal misoprostol appears to be more effective and less costy than dinoprostone which is administered intracervically or intravaginally, even though research based evidence in this issue show contradiction on the other hand researchers mention that dinoprostone appears to have a safer clinical profile due to lower frequency of uterine hyperstimulation and tachysystole .