PHOSPHORUS DISORDERS IN RELATION TO ANESTHESIA AND INTENSIVE CARE

Amir Kamal Eshak;

Abstract


Phosphorus is an important intracellular constituent. It is among the most abundant constituents of all tissues not only as a major component of the mineral phase of bone but of all tissues and in some form is involved in almost all metabolic processes.

Phosphate function is to store and to release energy via high-energy phosphates and is integral to the structure of proteins and lipids.

The amount of phosphorus m the normal adult is about 1000 g of which about 85% is in the skeleton. Normal range for phosphate is 2.7- 4.5 mg/dl in adults.

Total phosphorus levels are higher in children and tend to rise in women after the menopause.

There is a circadian variation of phosphate concentration even during a 24 hour fast, mediated in part by the adrenal cortex.

The homeostasis of phosphate is controlled by the parathyroid hormone, 1,25-dihydroxy cholecalciferol and calcitonin, and involves 3 main organs the intestine, the kidneys, and bone.

The main regulatory organ is the kidney. In its biological steady state, phosphate intake matches excretion.

Hypophosphatemia is usually subdivided into two categories moderate and severe hypophosphatemia; level of


Other data

Title PHOSPHORUS DISORDERS IN RELATION TO ANESTHESIA AND INTENSIVE CARE
Other Titles اضطرابات عنصر الفوسفور وعلاقتها بالتخدير والرعاية المركزة
Authors Amir Kamal Eshak
Issue Date 2002

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