TRANSCRANIAL DOPPLER AND CT ANGIOGRAPHY OF THE CEREBRAL ARTERIES IN EGYPTIAN SICKLE CELL PATIENTS

Abstract

To sum up,. Sickle cell disease (SCD) is one of the most common genetic diseases worldwide. It is a chronic haemolytic disorder that is marked by tendency of haemoglobin molecules within red cells to polymerise and deform the red cell into a shape resulting in characteristic vaso-occlusive events and accelerated haemolysis. Cerebrovascular accidents (CVA) are the most common cerebral insults reported in SCD patients caused by stenosis and occlusion of large vessels.