A Comparative Study of Two Different Treatment Protocols in Management of Male Patients with Hypogonadotropic Hypogonadism
Marwa Magdy Hassan Nawar;
Abstract
ABSTRACT
Hypogonadotropic hypogonadism (HH) is a disorder characterized by delayed puberty due to defective production of follicle stimulating hormone (FSH) and lutenizing hormone (LH) from the pituitary. HH can be due to congenital, idiopathic or acquired causes.
FSH is the major endocrine regulator of sertoli cell function and spermatogenesis. The sertoli cell is the only cell type in the testis that expresses receptors for FSH which is necessary for adequate sertoli cell proliferation and conditioning of spermatogonia. Sertoli cells produce and secrete inhibin B into the circulation as a response to FSH stimulation and inhibin B negatively regulates FSH.
Hypogonadotropic hypogonadism (HH) is a disorder characterized by delayed puberty due to defective production of follicle stimulating hormone (FSH) and lutenizing hormone (LH) from the pituitary. HH can be due to congenital, idiopathic or acquired causes.
FSH is the major endocrine regulator of sertoli cell function and spermatogenesis. The sertoli cell is the only cell type in the testis that expresses receptors for FSH which is necessary for adequate sertoli cell proliferation and conditioning of spermatogonia. Sertoli cells produce and secrete inhibin B into the circulation as a response to FSH stimulation and inhibin B negatively regulates FSH.
Other data
| Title | A Comparative Study of Two Different Treatment Protocols in Management of Male Patients with Hypogonadotropic Hypogonadism | Other Titles | دراسة مقارنة لاثنين من بروتوكولات العلاج المختلفة في علاج حالات قصور الغدد التناسلية النخامي لدي الذكور | Authors | Marwa Magdy Hassan Nawar | Issue Date | 2019 |
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