CONFOCAL AND ELECTRON MICROSCOPICAL STUDY OF THE CORNEA AFTER LASER IN SITU KERATOMILEUSIS(LASIK)
Sherif Hassan Emerah;
Abstract
Confocal microscopy is a noninvasive method that produces optical sections of corneal tissue and can be assembled to form an in vivo image with high resolution and contrast. It is an effective tool to examine healing processes in the cornea.
Laser In Situ Keratomiluesis (lASIK) is a technique to treat moderate and high myopia, involves lifting a corneal flap with a microkeratome and then ablating the stromal bed with an excimer laser to achieve refractive change. Recent clinical studies found that lASIK offers good efficacy, predictability, and safety in moderate and high myopia.
Our aim was to study the corneal wound healing after lASIK with confocal microscopy in human. We also studied the corneal healing in rabbits by confocal microscopy, light microscopy and electron microscopy. Finally, we tried to compare and correlate the findings between both humans and rabbits.
This work was done at Research Institute of Ophthalmology (RIO), Egypt and Louisiana State University eye center (LSU eye center), USA
In human study, Seventy-five eyes of 50 patients underwent lASIK procedure (45 eyes in RIO and 30 eyes in LSU eye center). Pre -operative complete ocular examination was done included uncorrected and best spectacle corrected visual acuity, manifest and cycloplegic refraction, slit lamp biomicroscopy, applanation tonometry, corneal pachymetry, corneal topography,
Laser In Situ Keratomiluesis (lASIK) is a technique to treat moderate and high myopia, involves lifting a corneal flap with a microkeratome and then ablating the stromal bed with an excimer laser to achieve refractive change. Recent clinical studies found that lASIK offers good efficacy, predictability, and safety in moderate and high myopia.
Our aim was to study the corneal wound healing after lASIK with confocal microscopy in human. We also studied the corneal healing in rabbits by confocal microscopy, light microscopy and electron microscopy. Finally, we tried to compare and correlate the findings between both humans and rabbits.
This work was done at Research Institute of Ophthalmology (RIO), Egypt and Louisiana State University eye center (LSU eye center), USA
In human study, Seventy-five eyes of 50 patients underwent lASIK procedure (45 eyes in RIO and 30 eyes in LSU eye center). Pre -operative complete ocular examination was done included uncorrected and best spectacle corrected visual acuity, manifest and cycloplegic refraction, slit lamp biomicroscopy, applanation tonometry, corneal pachymetry, corneal topography,
Other data
| Title | CONFOCAL AND ELECTRON MICROSCOPICAL STUDY OF THE CORNEA AFTER LASER IN SITU KERATOMILEUSIS(LASIK) | Other Titles | دراسة القرنيه باستخدام الميكروسكوب متطابق البؤرة والميكروسكوب الالكترونى بعد كشط القرنية وليزر اكزيمر داخلى | Authors | Sherif Hassan Emerah | Issue Date | 2002 |
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