Interrelationship between Chitotriosidase, Type 2 Diabetes Mellitus and Atherosclerosis
Amr Mahmoud Mohamed Abd El- Hady Saleh;
Abstract
T
ype-2 diabetes mellitus (T2DM) is the leading cause of cardiovascular morbidity and mortality worldwide. Poor glucose control, hypertension, and dyslipidemia are the main factors that increase the risk of atherosclerotic disease in T2DM.
Chitotriosidase, also named chitinase-1 (CHIT1), belongs to the 18 family of chitinases which is unexpectedly discovered in humans in the 1990s.
The exact function of human CHIT1 remains unclear, but its participation in process of inflammation and immune defense is postulated.
The present study was aiming to assess the relationship between Chitotriosidase level in patients with Type 2 Diabetes Mellitus and the development of atherosclerosis.
ype-2 diabetes mellitus (T2DM) is the leading cause of cardiovascular morbidity and mortality worldwide. Poor glucose control, hypertension, and dyslipidemia are the main factors that increase the risk of atherosclerotic disease in T2DM.
Chitotriosidase, also named chitinase-1 (CHIT1), belongs to the 18 family of chitinases which is unexpectedly discovered in humans in the 1990s.
The exact function of human CHIT1 remains unclear, but its participation in process of inflammation and immune defense is postulated.
The present study was aiming to assess the relationship between Chitotriosidase level in patients with Type 2 Diabetes Mellitus and the development of atherosclerosis.
Other data
| Title | Interrelationship between Chitotriosidase, Type 2 Diabetes Mellitus and Atherosclerosis | Other Titles | العلاقة بين الشيتوترايوسيداس وداء السكري من النوع الثاني وتصلب الشرايين | Authors | Amr Mahmoud Mohamed Abd El- Hady Saleh | Issue Date | 2019 |
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