Transmission of Cytomegalovirus Via Breast milk
Salwa Sobhy Ramadan;
Abstract
Breast fed infants are susceptible to HCMV infection from breast milk. HCMV particle shedding into whey may be more important in vertical infection by breast milk than cell-to-cell transmission.
This study was designed to evaluate HCMV transmission via breast milk to suckling infants. It was conducted on 90 infants aged 6-18 months. All were breast fed only from their own mothers or mixed fed. No history of previous blood or blood elements transfusion was given nor previous operations to any of the infants.
Eighty ofthe enrolled infants were full term and ten were preterm. Anti-CMV IgM was detected in the sera of
8 infants of the full term group (10%) and none in the sera of preterm infants which might be due to the small sample size of this group. From the milk samples of mothers of the 8 (10%) full term infants with positive CMV lgM, we detected CMV DNA by PCR in three milk samples from the 8 samples (37.5%).
The incidence of HCMV infection was found to be more among anemic infants and infants correlated positively with the order of birth.
There was no significant difference between male and female infants, low and middle socioeconomic
This study was designed to evaluate HCMV transmission via breast milk to suckling infants. It was conducted on 90 infants aged 6-18 months. All were breast fed only from their own mothers or mixed fed. No history of previous blood or blood elements transfusion was given nor previous operations to any of the infants.
Eighty ofthe enrolled infants were full term and ten were preterm. Anti-CMV IgM was detected in the sera of
8 infants of the full term group (10%) and none in the sera of preterm infants which might be due to the small sample size of this group. From the milk samples of mothers of the 8 (10%) full term infants with positive CMV lgM, we detected CMV DNA by PCR in three milk samples from the 8 samples (37.5%).
The incidence of HCMV infection was found to be more among anemic infants and infants correlated positively with the order of birth.
There was no significant difference between male and female infants, low and middle socioeconomic
Other data
| Title | Transmission of Cytomegalovirus Via Breast milk | Other Titles | انتقال عدوى الفيروس الخلوى العرطل عبر لبن الام | Authors | Salwa Sobhy Ramadan | Issue Date | 2002 |
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