Cord Thiobarbituric Acid Reactive Substances (TBARS) as a predictor for early onset sepsis in preterm

Abstract

The neonates under study (n = 80) were classified clinically and laboratory into 2 groups, Group A (Preterms with sepsis = 25 case) and Group B (Preterms with no sepsis= 55 case) regarding to clinical examination, different CBC parameters, 12h CRP & blood culture. Cord blood sample was collected from Group A (Preterms with sepsis = 25 case) &Group B (Preterms with no sepsis = 55 case) at birth and laboratory examined for thiobarbituric acid reactive species (TBARS, as a marker of lipid peroxidation). The average Cord TBARS ranged between 4.2 nmol/ml – 24 nmol/ml with Median 10.50 nmol/ml for sepsis group while the average Cord TBARS ranged between 0.5 nmol/ml – 17 nmol/ml with Median 3.00 for control group