Role of New Bone Markers in Diagnosis of Renal Osteodystrophy in Uremic Patients on Hemodialysis

Abstract

Renal osteodystrophy is a common fmding in patients with renal insufficiency, with maximal intensity being found in hem odialysis patients. Those patients lose their ability to excrete phosphate, produce calcitriol and maintain calcium balance. Left untreated, these abnormalities promote the development of secondary hyperparathyroidism. However, som treated patients develop bone abnormalities linked to oversuppression of bone turnover, identified with term(adynamic bone disease).