Prognostic Impact of KI67 in Localized Prostate Cancer
Asmaa Gamal Mohamed El Sayed;
Abstract
ABSTRACT
Background: disease heterogeneity is reflected by the diverse clinical courses of indolent, aggressive and lethal prostate cancers. Prostate cancer is the second most commonly diagnosed cancer and the second leading cause of cancer death in males, after lung cancer. Prostate cancer heterogenic presentation is reflected by the diverse clinical courses of indolent, aggressive and lethal disease, so searching for markers that work as a prognostic marker is mandatory to help in the decision of choosing the treatment modality. KI67 is a well-known tissue biomarker that has a prognostic impact in localized prostate cancer.
Aim of the work: The aim of the study is to correlate the percentage of expression of Ki67 with the biochemical failure, disease free survival, Gleason score and PSA level for localized prostate cancer patients.
Background: disease heterogeneity is reflected by the diverse clinical courses of indolent, aggressive and lethal prostate cancers. Prostate cancer is the second most commonly diagnosed cancer and the second leading cause of cancer death in males, after lung cancer. Prostate cancer heterogenic presentation is reflected by the diverse clinical courses of indolent, aggressive and lethal disease, so searching for markers that work as a prognostic marker is mandatory to help in the decision of choosing the treatment modality. KI67 is a well-known tissue biomarker that has a prognostic impact in localized prostate cancer.
Aim of the work: The aim of the study is to correlate the percentage of expression of Ki67 with the biochemical failure, disease free survival, Gleason score and PSA level for localized prostate cancer patients.
Other data
| Title | Prognostic Impact of KI67 in Localized Prostate Cancer | Other Titles | تاثير KI67 في سرطان البروستاتا الموضعى | Authors | Asmaa Gamal Mohamed El Sayed | Issue Date | 2019 |
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