Assessment of serum 25-hydroxy vitamin D in cirrhotic patients with and without spontaneous bacterial peritonitis
Ahmed Abd ElHakeem Mansour Amer;
Abstract
V
itamin D has pleiotropic functions. It is widely recognized to have a central role in calcium metabolism and bone mineralization. Vitamin D is also physiologically important for the proper function of organs such as skeletal muscle, heart, brain, and pancreas.
Vitamin D may also be implicated in innate and acquired immunity, it could increase innate defense and modulate the activation of lymphocytes implicated in the immune response, leading to a switch toward a T helper 2.
The frequent lack of vitamin D in cirrhotic patients has been known for a long time and could be partly due to liver insufficiency (which could decrease the rate of hydroxylation of cholecalciferol) and cholestasis (which impairs the absorption of fat-soluble vitamins).
itamin D has pleiotropic functions. It is widely recognized to have a central role in calcium metabolism and bone mineralization. Vitamin D is also physiologically important for the proper function of organs such as skeletal muscle, heart, brain, and pancreas.
Vitamin D may also be implicated in innate and acquired immunity, it could increase innate defense and modulate the activation of lymphocytes implicated in the immune response, leading to a switch toward a T helper 2.
The frequent lack of vitamin D in cirrhotic patients has been known for a long time and could be partly due to liver insufficiency (which could decrease the rate of hydroxylation of cholecalciferol) and cholestasis (which impairs the absorption of fat-soluble vitamins).
Other data
| Title | Assessment of serum 25-hydroxy vitamin D in cirrhotic patients with and without spontaneous bacterial peritonitis | Other Titles | تقييم المصل 25-هيدروكسي فيتامين D في مرضى التليف الكبدى مع وبدون التهاب الغشاء البريتونى الجرثومي العفوي | Authors | Ahmed Abd ElHakeem Mansour Amer | Issue Date | 2019 |
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