p53 TUMOR SUPPRESSOR GENE IN MENINGIOMA
Khaled Mohamed Fathy Saoud;
Abstract
Although meningiomas which represent
15.20% of primary brain tumors are considered benign tumors, yet clinically aggressive forms do occur causing recurrence.
The histopathological examination of these tumors failed to predict the biological behavior, aggressiveness and recurrences of these tumors.
Association of p53 gene abnormalities with tumor progression and prognosis of many tumors have been demonstrated, but little is known about the clinical significance of p53 abnormalities in
meningiomas.
The diagnosis and classification of meningiomas still often relay on microscopic examination of tissue by routine staining methods
which is unfortunate,of limited prognostic value.
15.20% of primary brain tumors are considered benign tumors, yet clinically aggressive forms do occur causing recurrence.
The histopathological examination of these tumors failed to predict the biological behavior, aggressiveness and recurrences of these tumors.
Association of p53 gene abnormalities with tumor progression and prognosis of many tumors have been demonstrated, but little is known about the clinical significance of p53 abnormalities in
meningiomas.
The diagnosis and classification of meningiomas still often relay on microscopic examination of tissue by routine staining methods
which is unfortunate,of limited prognostic value.
Other data
| Title | p53 TUMOR SUPPRESSOR GENE IN MENINGIOMA | Other Titles | الدور الإكلينيكى للجين المثبط للأورام ( ب53) فى الأورام السحائية | Authors | Khaled Mohamed Fathy Saoud | Issue Date | 2000 |
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