Short-term Outcome of Manual Thrombus Aspiration for Patients Undergoing Primary PCI for Acute STEMI Showing Large Thrombus Burden

Abstract

currently the preferred treatment & the default strategy. Several studies have shown that manual aspiration of the thrombus during primary PCI can prevent distal embolization, improve myocardial reperfusion and improve clinical outcome. There is a controversy in many clinical trials for the use of the aspiration devices during primary percutaneous coronary intervention (PPCI) in patients presented with acute ST segment elevation myocardial infarction (STEMI). The purpose of the current study was to determine the efficacy of thrombus extraction as adjunctive treatment before angioplasty for STEMI patients , with evidence of heavy thrombus burden , regarding MACE (primary end-points ) & secondary end-points (TIMI flow ,MBG , STsegment resolution , LV systolic function )as well as to determine 1 month follow-up results. Two hundred and nine patients were enrolled in the current study with diagnosis of acute STEMI , and planned for primary PCI & with evidence of heavy thrombus burden. Primary PCI with aspiration thrombectomy was done for 73 patients and conventional primary PCI (without aspiration thrombectomy) was done for 136 patients.