Menopause in an Egyptian cohort of Systemic Lupus Erythematosus: Effect of the disease
Marina Waguih Naguib Gerges;
Abstract
SLE is an important prevalent chronic autoimmune
disease with female to male preponderance of 9:1. SLE is
characterized by the production of pathogenic
autoantibodies, primarily to nuclear antigens, as well as
dysregulation of both T and B cells.
Treatment of the disease involves powerful
immunosuppressive medications such as steroids and
cyclophosphamide, which have been implicated with
ovarian failure and premature menopause. It has been
speculated that disease activity is altered in different age
spectrums and menstrual status.
disease with female to male preponderance of 9:1. SLE is
characterized by the production of pathogenic
autoantibodies, primarily to nuclear antigens, as well as
dysregulation of both T and B cells.
Treatment of the disease involves powerful
immunosuppressive medications such as steroids and
cyclophosphamide, which have been implicated with
ovarian failure and premature menopause. It has been
speculated that disease activity is altered in different age
spectrums and menstrual status.
Other data
| Title | Menopause in an Egyptian cohort of Systemic Lupus Erythematosus: Effect of the disease | Other Titles | انقطاع الطمث فى مجموعة من مرضى الذئبة الحمراء فى المصر ياٌت: دراسة تأثيرٌ المرض | Authors | Marina Waguih Naguib Gerges | Issue Date | 2018 |
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