A Comparative Study of the Diagnostic and Prognostic Value of Golgi Protein 73 and Alfa-feto Protein in Hepatocellular Carcinoma Before and After Therapeutic Intervention

Abstract

epatocellular carcinoma (HCC) is one of the most common tumors and fatal malignancies worldwide, and its incidence is increasing. It is associated with chronic, persistent infection of hepatitis B virus (HBV) or hepatitis C virus (HCV) as well as non-virus etiologies, including alcohol, chemicals, and aflatoxin B1. Most HCC patients are usually asymptomatic until the late stages, when patients with obvious clinical symptoms come to the hospital for treatment, the HCC has already reached the advanced stages and is usually large in size. Given the subsequent rapid growth and vascular invasion, the prognosis then is very poor.