URINARY TRANSFORMING GROWTH FACTOR B-1 IN NEPHROTIC CHILDREN
SAKINA ABDUL WASSA MOHAMED GHALEB;
Abstract
Nephrotic syndrome is one of the most important renal disorders in childhood and it may end with chronic renal failure, TGF- 1 is a multi functional cytokine
that plays an important role in glomerulosclerosis that leads to chronic renal failure .
This study aimed at evaluating the role of
estimation ofTGF- 1 in urine of nephrotic children as a parameter of progression of the disease and a predictor of response to steroid therapy.
•Forty-four children attending the Nephrology Unit
of Ain Shams University Children's Hospital were
',: enrolled in the study, 30 with INS and 14 with ESRD under regular haemodialysis and were compared to 30 normal, age and sex matched controls. The nephrotic children were divided according to their response to • steroid therapy into 13 dependent and 10 resistant cases. In addition to 7 newly diagnosed nephrotic children who were sampled at presentation and after one month of steroid therapy.
All patients were subjected to history taking, stressing on duration of illness, drug history and dose of
that plays an important role in glomerulosclerosis that leads to chronic renal failure .
This study aimed at evaluating the role of
estimation ofTGF- 1 in urine of nephrotic children as a parameter of progression of the disease and a predictor of response to steroid therapy.
•Forty-four children attending the Nephrology Unit
of Ain Shams University Children's Hospital were
',: enrolled in the study, 30 with INS and 14 with ESRD under regular haemodialysis and were compared to 30 normal, age and sex matched controls. The nephrotic children were divided according to their response to • steroid therapy into 13 dependent and 10 resistant cases. In addition to 7 newly diagnosed nephrotic children who were sampled at presentation and after one month of steroid therapy.
All patients were subjected to history taking, stressing on duration of illness, drug history and dose of
Other data
| Title | URINARY TRANSFORMING GROWTH FACTOR B-1 IN NEPHROTIC CHILDREN | Other Titles | عامل النمو التحويلى بيتا واحد فى بول الاطفال المصابين بمتلازمة النفروز | Authors | SAKINA ABDUL WASSA MOHAMED GHALEB | Issue Date | 2000 |
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