STUDY OF SERUM VITAMIN D LEVELS AMONGST HIP FRACTURES IN ELDERLY
Abeer Abdelzaher Abdallah;
Abstract
Bone mineral density decreases with age, and several studies documented the evidence that bone loss persists in the elderly. As a result of persisting bone loss, hip fractures in elderly are rather common and represent a major public health problem (Garnero et aL, 1996).
Vitamin D deficiency, which causes osteomalacia, may also be important in the pathogenesis of age-related osteoprosis. There is a decline in serum 25 hydroxy vitamin D, 1-25 dihydroxy vitamin D, and calcium absorption with advancing age, which may lead to secondary hyperparathyroidism and bone loss (Francis RM., 1997).
Studies show a relationship between serum 25 hyroxy vitamin D and bone density in older men and women, with an iverse correlation between bone density and parathroid hormone (PTH). Vitamin D supplementation in this age group improves calcium absorption, supresses (PTH) and decreases bone loss. Vitamin D may also reduces the incidence of hip and other non vertebral fractures, particularly in elderly who are likely to have vitamin D deficiency (Francis RM., 1997).
The relative importance of vitamin D deficiency and low bone mineral density, as risk factors for hip fractures are not definitely established (Thiebaud et aL, 1997). Consquently, this study was conducted to prove this importance.
In this work we were aiming to detect occult (subclinical) vitamin D deficiency in elderly men and women with hip fracture in order to prevent these devastating fractures.
Vitamin D deficiency, which causes osteomalacia, may also be important in the pathogenesis of age-related osteoprosis. There is a decline in serum 25 hydroxy vitamin D, 1-25 dihydroxy vitamin D, and calcium absorption with advancing age, which may lead to secondary hyperparathyroidism and bone loss (Francis RM., 1997).
Studies show a relationship between serum 25 hyroxy vitamin D and bone density in older men and women, with an iverse correlation between bone density and parathroid hormone (PTH). Vitamin D supplementation in this age group improves calcium absorption, supresses (PTH) and decreases bone loss. Vitamin D may also reduces the incidence of hip and other non vertebral fractures, particularly in elderly who are likely to have vitamin D deficiency (Francis RM., 1997).
The relative importance of vitamin D deficiency and low bone mineral density, as risk factors for hip fractures are not definitely established (Thiebaud et aL, 1997). Consquently, this study was conducted to prove this importance.
In this work we were aiming to detect occult (subclinical) vitamin D deficiency in elderly men and women with hip fracture in order to prevent these devastating fractures.
Other data
| Title | STUDY OF SERUM VITAMIN D LEVELS AMONGST HIP FRACTURES IN ELDERLY | Other Titles | دراسة مستويات فيتامين (د) فى الدم بين حالات كسور العظام الحرقفية عند المسنين | Authors | Abeer Abdelzaher Abdallah | Issue Date | 2002 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.