PET/CT implication on bronchogenic carcinoma TNM staging and follow-up using RECIST/PERCIST criteria: a comparative study with CT
Ahmed Osman; Hazem I. Korashi;
Abstract
© 2020, The Author(s). Background: To evaluate the role of PET/CT on bronchogenic carcinoma staging as well as treatment response evaluation on follow-up compared to CT study alone. Methods: A prospective study of 60 patients confirmed histopathologically to have non-small cell bronchogenic carcinoma, 30 of them came for staging (group T) while the rest 30 came for follow-up (group F) to assess therapy response. All patients underwent PET/CT with data analysis done using the eighth edition tumor, nodal, metastatic staging (TNM) staging for group T and RECIST/PERCIST criteria for group F. The CT data alone transferred to a blind radiologist for analysis using the same parameters. The results were collected and compared. Results: Regarding group T, 12 patients showed different TNM staging between PET/CT and CT alone, 5 cases with different T stagings, 4 cases with different N stagings, and 5 cases with different M stagings. Also, 8 cases showed different surgical stagings. Regarding group F, 9 cases showed a difference between RECIST obtained by CT and PERCIST obtained by PET/CT with most of the cases (6 cases) showed change from partial or stable response to progressive response. Conclusion: PET/CT has a significant role in TNM staging of bronchogenic carcinoma more at T2 staging due to its ability to differentiate the tumoral mass from the nearby pulmonary reaction. Also, PET/CT makes a difference in tumoral follow-up by its ability to detect the functional changes even before structural changes. Finally, PET/CT is a very important tool in management strategy.
Other data
Title | PET/CT implication on bronchogenic carcinoma TNM staging and follow-up using RECIST/PERCIST criteria: a comparative study with CT | Authors | Ahmed Osman ; Hazem I. Korashi | Keywords | POSITRON-EMISSION-TOMOGRAPHY;CELL LUNG-CANCER;COMPUTED-TOMOGRAPHY;RESPONSE CRITERIA;IMPACT;MANAGEMENT;PERCIST;SURVIVAL;PREDICTION;RECIST | Issue Date | 2020 | Publisher | SPRINGEROPEN | Journal | Egyptian Journal of Radiology and Nuclear Medicine | ISSN | 0378603X | DOI | 1 http://dx.doi.org/10.1186/s43055-020-0133-5 51 10.1186/s43055-020-0133-5 |
Scopus ID | 2-s2.0-85077904595 | Web of science ID | WOS:000521271000003 |
Attached Files
File | Description | Size | Format | Existing users please Login |
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10- PET CT impication on bronchogenic carcinoma EJRNM.pdf | 7.55 MB | Adobe PDF | Request a copy | |
14- PET CT impication on bronchogenic carcinoma EJRNM.pdf | 7.55 MB | Unknown | Request a copy |
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