Bioactive compounds, antioxidant potential, and hepatoprotective activity of sea cucumber (Holothuria atra) against thioacetamide intoxication in rats

Esmat, Amr Y; Said, Mahmoud M; Soliman, Amel A; El-Masry, Khaled S H; Abdel-Badiea, Elham;

Abstract


The identification of the active phenolic compounds in the mixed extract of sea cucumber (Holothuria atra) body wall by high-performance liquid chromatography and an assessment of its hepatoprotective activity against thioacetamide-induced liver fibrosis in rats.


Other data

Title Bioactive compounds, antioxidant potential, and hepatoprotective activity of sea cucumber (Holothuria atra) against thioacetamide intoxication in rats
Authors Esmat, Amr Y; Said, Mahmoud M; Soliman, Amel A; El-Masry, Khaled S H; Abdel-Badiea, Elham 
Keywords Holothuria atra extract; High-performance liquid chromatographic analysis; In vitro antioxidant studies; Thioacetamide; Liver function tests; Antioxidant enzymes; Histologic studies; Rats; LIPID-PEROXIDATION PRODUCTS; INDUCED LIVER FIBROSIS; COLORIMETRIC METHOD; HEPATIC-FIBROSIS; OXIDATIVE STRESS; TEA CATECHINS; IN-VITRO; ENZYMES; MICE; DNA
Issue Date Jan-2013
Publisher ELSEVIER SCIENCE INC
Journal Nutrition (Burbank, Los Angeles County, Calif.)
ISSN 0899-9007
DOI 10.1016/j.nut.2012.06.004
PubMed ID 23085016
Web of science ID WOS:000313138200040

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