Effect of cyclosporine A versus tacrolimus on the response to antiviral therapy after hepatitis C genotype-4 recurrence post-liver transplantation: A prospective cohort trial
El-Hamamsy, Manal; Montasser, Iman; Mansy, Azza El-Sayed; Nabet, Dina; El-Meteini, Mahmoud;
Abstract
The influence of immunosuppression on the response to antiviral therapy (AVT) for recurrent hepatitis C virus (HCV) infection in liver transplant (LT) recipients remains controversial, especially for the rarely investigated genotype 4. This study aims to compare the effects of the two widely used calcineurin inhibitors (CNIs) (cyclosporine A (CsA) and tacrolimus (Tac)) on the therapeutic response to different AVT regimens.
Other data
| Title | Effect of cyclosporine A versus tacrolimus on the response to antiviral therapy after hepatitis C genotype-4 recurrence post-liver transplantation: A prospective cohort trial | Authors | El-Hamamsy, Manal ; Montasser, Iman ; Mansy, Azza El-Sayed; Nabet, Dina ; El-Meteini, Mahmoud | Affiliations | Faculty of Medicine | Keywords | antiviral therapy; calcineurin inhibitors; hepatitis C genotype-4; liver transplantation; sustained virological response | Issue Date | Jun-2019 | Publisher | WILEY | Journal | Journal of clinical pharmacy and therapeutics | ISSN | 0269-4727 | DOI | 10.1111/jcpt.12807 | PubMed ID | 30714175 | Scopus ID | 2-s2.0-85060971107 | Web of science ID | WOS:000465298300014 |
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