Studies on the Chemical Reactions of Some 3-Substituted-6,8-dimethylchromones with Nucleophilic Reagents
Magdy A. Ibrahim; Nasser M. El-Gohary; S.H. Hashiem; Al-Shimaa Badran;
Abstract
A variety of 3-substituted-6,8-dimethylchromones have been synthesized and characterized. The chemical reactivity of 3-substituted-6,8-dimethylchromones was studied towards some nucleophiles, namely, S-benzyldithiocarbazate, o-phenylenediamine, and cyanoacetamide, and a diversity of products were efficiently synthesized. Reactions of 3-substituted-6,8-dimethylchromones (except 3-formyl-6,8-dimethylchromone), with nucleophilic reagents, usually proceed through nucleophilic attack at C-2 position followed by different types of heterocyclization depending on the functional group present at C-3 position. Structures of the newly synthesized products have been established based on elemental analysis and spectral data.
Other data
Title | Studies on the Chemical Reactions of Some 3-Substituted-6,8-dimethylchromones with Nucleophilic Reagents | Authors | Magdy A. Ibrahim ; Nasser M. El-Gohary; S.H. Hashiem; Al-Shimaa Badran | Keywords | 3-Substituted-6,8-dimethylchromones | Issue Date | 2018 | Publisher | Wiley | Journal | Journal of Heterocyclic Chemistry | Volume | 55 | Issue | 10 | Start page | 2315 | End page | 2324 | DOI | 10.1002/jhet.3291 |
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