Novel heterocyclic derivatives of pyrano[3,2‐c]quinolinone from 3‐(1‐ethy1‐4‐hydroxy‐2‐oxo‐2(1H)‐quinolin‐3‐yl)‐3‐oxopropanoic acid
Magdy A. Ibrahim; Hany Hassanin; Yassin Gabr; Y. A. Allnamer;
Abstract
3‐(1‐Ethyl‐4‐hydroxy‐2‐oxo‐2(1H)‐quinolin‐3‐yl)‐3‐oxopropanoic acid (2) has been
synthesized. The chemical behaviour of β‐ketoacid 2 was studied towards condensation
reactions with salicylaldelyde, 2‐hydroxy‐1‐naphthaldehyde, 1‐phenyl‐4‐hydroxy‐2‐oxoquinoline‐
3‐carboxaldehyde, 2‐hydroxy‐4‐oxo‐4H‐pyrido[1,2‐a]pyrimidine‐3‐carboxaldehyde,
2‐amino‐3‐formylchromone and its 8‐allyl analog, 3‐cyanochromone and its 8‐allyl
analog. Structures of the newly synthesized products have been deduced from their elemental
analysis and spectral data.
synthesized. The chemical behaviour of β‐ketoacid 2 was studied towards condensation
reactions with salicylaldelyde, 2‐hydroxy‐1‐naphthaldehyde, 1‐phenyl‐4‐hydroxy‐2‐oxoquinoline‐
3‐carboxaldehyde, 2‐hydroxy‐4‐oxo‐4H‐pyrido[1,2‐a]pyrimidine‐3‐carboxaldehyde,
2‐amino‐3‐formylchromone and its 8‐allyl analog, 3‐cyanochromone and its 8‐allyl
analog. Structures of the newly synthesized products have been deduced from their elemental
analysis and spectral data.
Other data
| Title | Novel heterocyclic derivatives of pyrano[3,2‐c]quinolinone from 3‐(1‐ethy1‐4‐hydroxy‐2‐oxo‐2(1H)‐quinolin‐3‐yl)‐3‐oxopropanoic acid | Authors | Magdy A. Ibrahim ; Hany Hassanin; Yassin Gabr; Y. A. Allnamer | Issue Date | Jun-2010 | Publisher | European Journal Chemistry | Volume | 3 | Start page | 195 | End page | 199 |
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