Substituted quinolinones, part 11: Efficient synthesis of different 3-(4-arylidene and hetarylidene-5-oxopyrazolin-3-yl) quinolin-2-ones
Othman,E.S.; Mohamed Abass; Akram Hassan;
Abstract
Several 3-(4-arylidene and hetarylidene-5-oxopyrazolin-3-yl)quinolin-2-ones
6–26 were synthesized in an efficient methodology utilizing both pyrazolinylquinolinone
2 and its chromenylmethylene derivative 10. Compound 2 was derivatized by Knoevenagel
condensation with different carbonyl compounds. Nucleophilic ring opening–ring
closure (RORC) of the compound 10 furnished the desired 4-methylenepyarzolinone
bearing novel five-, six-, and seven-membered heterocycles, in good yields.
6–26 were synthesized in an efficient methodology utilizing both pyrazolinylquinolinone
2 and its chromenylmethylene derivative 10. Compound 2 was derivatized by Knoevenagel
condensation with different carbonyl compounds. Nucleophilic ring opening–ring
closure (RORC) of the compound 10 furnished the desired 4-methylenepyarzolinone
bearing novel five-, six-, and seven-membered heterocycles, in good yields.
Other data
| Title | Substituted quinolinones, part 11: Efficient synthesis of different 3-(4-arylidene and hetarylidene-5-oxopyrazolin-3-yl) quinolin-2-ones | Authors | Othman,E.S. ; Mohamed Abass; Akram Hassan | Issue Date | 2007 | Publisher | Taylor & Francis Group | Volume | 37 | Issue | 4 | Start page | 607 | End page | 621 |
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