Substituted quinolinones Part 23. Synthesis of 6 ethyl 4,5 dioxo 5,6 dihydro 4 H pyrano[3,2 c ]quinoline 3 carboxaldehyde and its chemical behavior towards hydroxylamine hydrochloride
Magdy A. Ibrahim; Al-Shimaa Badran; Mohamed Abass; Hany M. Hassanin;
Abstract
The synthesis of novel 6-ethyl-4,5-dioxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-3-carbox-aldehyde is described via Vilsmeier-Haack reaction of 3-acetyl-1-ethyl-4-hydroxyquinolin-2(1H)-one. The reaction of titled aldehyde with hydroxylamine hydrochloride, under different conditions, revealed its distinctive chemical behavior and a variety of products were obtained. This study revealed existence of ring-opening ring-closure (RORC) on treatment with hydroxylamine hydrochloride in both acetic acid and/or ethanolic potassium hydroxide. The structure of the new products was deduced on basis of their analytical and spectral data.
Other data
Title | Substituted quinolinones Part 23. Synthesis of 6 ethyl 4,5 dioxo 5,6 dihydro 4 H pyrano[3,2 c ]quinoline 3 carboxaldehyde and its chemical behavior towards hydroxylamine hydrochloride | Authors | Magdy A. Ibrahim; Al-Shimaa Badran ; Mohamed Abass; Hany M. Hassanin | Keywords | Pyrano[3,2-c]quinoline | Issue Date | 2013 | Publisher | ARKAT USA, Inc. | Journal | Arkivoc | Volume | iv | Start page | 424 | End page | 431 | DOI | 10.3998/ark.5550190.p008.265 |
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