Peripheral embolization following thrombolytic therapy for acute ischemic stroke—a case report

roushdy, tamer; Hamid, Eman; Fathy, Mai; Bastawy, Islam; Aref, Hany; El Nahas, Nevine;

Abstract


Background: Intravenous recombinant tissue plasminogen activator is the only golden approved medical therapy for
acute ischemic stroke, guidelines for its injection relay on reducing or preventing associated hemorrhage as a side
effect, yet hemorrhage is not the only possible complication, further embolization following injection is also a
possibility; in this case report, peripheral embolization following intravenous recombinant tissue plasminogen activator
with two possible explanations one related to the treatment and another related to the patient liability is represented.

Case presentation: A 78-year-old male presenting with acute onset of stroke, received intravenous recombinant tissue
plasminogen activator, 16 h later he developed acute limb ischemia.

Conclusion: Peripheral embolization may happen within hours from intravenous recombinant tissue plasminogen
activator administration.


Other data

Title Peripheral embolization following thrombolytic therapy for acute ischemic stroke—a case report
Authors roushdy, tamer ; Hamid, Eman; Fathy, Mai; Bastawy, Islam; Aref, Hany ; El Nahas, Nevine 
Keywords Thrombolytic therapy;Acute stroke;Peripheral embolization,;Intra-cardiac thrombus
Issue Date 8-Oct-2020
Publisher Springer Open
Journal The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 
Volume 56
Issue 99
ISSN 1687-8329
DOI 10.1186/s41983-020-00231-x
Scopus ID 2-s2.0-85092194698
Web of science ID WOS:000576168900001

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