Effect of direct-acting antivirals on corrected QT interval and cardiac functions in patients with chronic hepatitis C virus infection

Ibrahim, Mohamed Gamal; Sharafeldin, Ahmed Abdelrahman; Mousa, Nevine Ibrahim; Mousa, Tarek Khairy; El Missiri, Ahmed;

Abstract


Hepatitis C virus (HCV) infection is a major public health problem in Egypt. The use of direct-acting antivirals (DAAs) in such patients has been shown to be highly effective. The cardiac safety of such antivirals remains uncertain. This study aimed to assess the effect of the novel DAAs on corrected QT (QTc) interval and on cardiac function using trans-thoracic echocardiography.


Other data

Title Effect of direct-acting antivirals on corrected QT interval and cardiac functions in patients with chronic hepatitis C virus infection
Authors Ibrahim, Mohamed Gamal; Sharafeldin, Ahmed Abdelrahman; Mousa, Nevine Ibrahim; Mousa, Tarek Khairy; El Missiri, Ahmed 
Keywords Cardiac function;Hepatitis C virus;Echocardiography;Direct-acting antiviral
Issue Date 7-Feb-2020
Journal The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology 
ISSN 2090-911X
DOI 10.1186/s43044-020-0042-y
PubMed ID 32030482

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