Some nucleophilic cyclization reactions with 3-[4-(benzo[1,3]dioxolylmethylene)pyrazolyl]quinolone

Abstract

Cyclization of 3-[4-(Benzo[1,3]dioxolylmethylene)-5-oxo-3-pyrazolyl]-4-hydroxy-1-methyl-quinolin-2(1H)-one with certain bifunctional nucleophilic reagents is described. The cyclization reactions led to the formation of many biologically interesting fused heterocyclic systems derived from pyrazolinone and bearing quinolinone moiety e.g. pyrazolopyrazole, isoxazolopyrazole, pyrazolopyrimidine, pyrazolothiazine, pyrazolopyridine, dipyrazolo-pyridine, dipyrazolopyran and many pyrazolopyran derivatives. The structures of all the new products were checked with analytical and spectral methods