Efficacy and Safety of Magnesium versus Dexmedetomidine as Additives to Local Anesthetic Mixture Using Single Injection Percutaneous Peribulbar Anesthesia in Vitreoretinal Surgeries
SOBHY, AMR;
Abstract
Background:
Peribulbar block for vitreoretinal surgery is rather associated with delayed onset of globe anesthesia, akinesia and short duration of
analgesia.
Objective:
To compare the effect of addition of Magnesium sulphate vs dexmedetomidine to standard local anesthetics mixtures on the time of
onset of Globe Anesthesia, Akinesia & analgesia duration.
Patients and Methods:
Ninety patients of both sexes, aged 25- 75 years, ASA I-III scheduled for vitreoretinal surgery. They were randomly allocated into 3
equal groups each received peribulbar block a mixture of Levo- bupivacaine 0.5% (3 ml) + lidocaine 2% (3 ml) +120 IU
hyaluronidase + Control group (C): 0.5 ml of Normal saline. Group (M): 50 mg of Magnesium sulphate in 0.5 ml normal saline.
Group (D): 50 μic of dexmedetomidine in 0.5 ml normal saline. The duration of sensory, motor block, Sedation level, Intra-ocular
Pressure (IOP) and surgeon satisfaction were assessed.
Results:
The onset of globe anesthesia and akinesia was significantly shorter in M group in comparison with D and C Groups, with a
significant increase in the duration of globe analgesia and akinesia in the D Group when compared to both M & C groups. Groups D
and M showed a statistically significant decrease in the IOP at 5 min and 10 min when compared to the baseline measurement of the
same groups & to C Group, no complications or adverse effects related to the drug or technique were recorded.
Conclusion:
Magnesium sulphate as a local anesthetic adjuvant in peribulbar block is safe and comparable to dexmedetomidine regarding the
sensory and motor block duration with better cost-effectiveness and availability.
Peribulbar block for vitreoretinal surgery is rather associated with delayed onset of globe anesthesia, akinesia and short duration of
analgesia.
Objective:
To compare the effect of addition of Magnesium sulphate vs dexmedetomidine to standard local anesthetics mixtures on the time of
onset of Globe Anesthesia, Akinesia & analgesia duration.
Patients and Methods:
Ninety patients of both sexes, aged 25- 75 years, ASA I-III scheduled for vitreoretinal surgery. They were randomly allocated into 3
equal groups each received peribulbar block a mixture of Levo- bupivacaine 0.5% (3 ml) + lidocaine 2% (3 ml) +120 IU
hyaluronidase + Control group (C): 0.5 ml of Normal saline. Group (M): 50 mg of Magnesium sulphate in 0.5 ml normal saline.
Group (D): 50 μic of dexmedetomidine in 0.5 ml normal saline. The duration of sensory, motor block, Sedation level, Intra-ocular
Pressure (IOP) and surgeon satisfaction were assessed.
Results:
The onset of globe anesthesia and akinesia was significantly shorter in M group in comparison with D and C Groups, with a
significant increase in the duration of globe analgesia and akinesia in the D Group when compared to both M & C groups. Groups D
and M showed a statistically significant decrease in the IOP at 5 min and 10 min when compared to the baseline measurement of the
same groups & to C Group, no complications or adverse effects related to the drug or technique were recorded.
Conclusion:
Magnesium sulphate as a local anesthetic adjuvant in peribulbar block is safe and comparable to dexmedetomidine regarding the
sensory and motor block duration with better cost-effectiveness and availability.
Other data
Title | Efficacy and Safety of Magnesium versus Dexmedetomidine as Additives to Local Anesthetic Mixture Using Single Injection Percutaneous Peribulbar Anesthesia in Vitreoretinal Surgeries | Authors | SOBHY, AMR | Keywords | Magnesium sulphate;Local anesthetic adjuvant;Vitreoretinal surgeries;Single injection;Peribulbar block;Dexmedetomidine | Issue Date | 20-Dec-2018 | Publisher | Bentham Open | Journal | Open Anesthesia Journal | Volume | 12 | Start page | 94 | End page | 100 | DOI | 10.2174/2589645801812010094 |
Attached Files
File | Description | Size | Format | Existing users please Login |
---|---|---|---|---|
opthalmic.pdf | Magnesium versus Dexmedetomidine as Additives to Local Anesthetic Mixture Using Single Injection Percutaneous Peribulbar Anesthesia in Vitreoretinal Surgeries | 232.84 kB | Adobe PDF | Request a copy |
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.