BIO EFFECTS OF EXTRACORPOREAL SHOCK WAVE LITHOTRIPSY(ESWL) FOR TREATMENT OF RENAL STONES

Abstract

Extracorporeal shock wave lithotripsy (ESWL) ts a non-mvastve treatment for urinary calculi, characterized by high success rate, few complications, low morbidity and short hospital stay and outpatient therapy . with resulting lower costs.

The persent study included 64 patients, classified into two groups adult group of 49 patients and children group of 15 patients, stone burden for those patients were either single, 2 stones or multiple stones with variable size from >10 mm to <25 mm.

ESWL was performed by modefied Domier MPL 9000 at ESWL Unit

Assiut University Hospital with a mean number of shock waves less than 3200

SW delivered at low energy 14-18 kilovoltage, regardless of time of exposure, disintigration results or clearance of stones. This present study was done only only patients treated with ESWL for the first time and for one sission only.

For those patients urine and blood samples were taken before one day

• and one month after ESWL. These samples were provided for the following investigations:

1- Urinary markers:

-Nacetyl B-glucose aminidase (NAG)

-a1-microglobulin (a1 MG)

-Brmicroglobulin (B2 MG)

2- Plasma renin activity (PRA)

3- Serum parathyroid hormone(PTH)