Comparison between the Incidence of Coronary No-Reflow in Patients with Acute ST-Elevation Myocardial Infarction Receiving Ticagrelor versus Clopidogrel Loading Doses

Abstract

Abstract The primary endpoint of no reflow occurred in 17 (34%) patients in the clopidogrel group versus 12 (24%) patients in the ticagrelor group. This difference was not statistically significant. The main findings in our study are the following:  There was no significant difference between the 2 groups in terms of epicardial coronary flow defined by TIMI flow.  There was no significant difference between the 2 groups in terms of myocardial perfusion defined by MBG.  There was no significant difference between the 2 groups as regards the primary endpoint of CNR defined as a TIMI flow<3 and/or an MBG of 0-1.  There was no significant difference between the 2 groups in terms of short term clinical outcomes of death, non-fatal MI, myocardial contractility, repeat revascularization and stroke.