Level of Vitamin D3 in Women who have Uterine Fibroids

Abstract

terine fibroid are benign smooth muscle tumors of the uterus. They are the most common benign pelvic tumors among women in reproductive age group and are not observed in pre-pubescent girls, indicating that tumor origin depends on hormonal changes. They are clinically diagnosed in 20- 30 % of women and established at autopsy in an additional 20-30. The origin of UFs is multifactorial and its exact pathophysiology is still unknown. The known underlined risk factors which increase the incidence of UF are: black race, elevated body mass index (BMI), age, positive family history, early menarche, hypertension, time elapsed since last labor, diet containing high amount of red meat. In recent years, significant progress has been made in understanding the basic mechanism of initiation and development of leiomyoma.