Impact of Diabetes Mellitus on Pulmonary Functions in COPD Patients

Abstract

hronic obstructive pulmonary disease (COPD) is a disease state characterized by progressive airflow limitation and is associated with an abnormal inflammatory response of the lungs to noxious particles or gases, primarily caused by cigarette smoking DM affects 1.6 to 16% of subjects with COPD. Metabolic syndrome, insulin resistance and systemic inflammation constitute risk factors for decreased lung function in healthy non-smoking subjects which suggest that even in the absence of smoking, DM can lead to similar effects on pulmonary function