Evaluation of the effect of sildenafil in hemodialysis patients with pulmonary Hypertension.

Abstract

Excess mortality rates due to cardiovascular disease in end- stage renal disease (ESRD) patients was described by many epidemiological and clinical studies.. Pulmonary hypertension is a Patho-physiological disorder that involves multiple clinical conditions and can complicate many cardiovascular and respiratory diseases .

The aim of our study was to evaluate the effect of sildenafil on pulmonary artery pressure in hemodialysis patients with pulmonary hypertension by measuring the reduction in estimated Pulmonary Artery pressure value (ePAP) via transthoracic Doppler Echocardiography and evaluate clinical improvement via six minute walk test (6MWT).