Objective and Subjective Outcome of Corneal Collagen Cross Linking in keratoconic patients according to keratoconus grading

Abstract

The cornea represents a transparent avascular connective tissue that has a primary infection and structural barrier function. With the overlying tear film, it forms the anterior refractive surface of the eye optical system 1. Any disruption of the corneal fiber network can result in decreased structural integrity of the cornea, leading to decreased vision. One of the diseases that exhibit these pathological changes is keratoconus. Keratoconus is a non-inflammatory bilateral progressive but asymmetrical disease. Described as corneal ectasia, thinning, gradual corneal protrusion and irregular astigmatism 2. It usually starts during puberty with 75% of cases diagnosed before the age of 25 years 3. Visual correction of early keratoconus may be achieved with spectacles and a large proportion of cases with advanced keratoconus may be correctable with rigid contact lenses. Surgical intervention is necessary when conservative management fails to achieve adequate visual rehabilitation. 4