Central venous oxygen saturation as predictor of failure of weaning from mechanical ventilation

Abstract

Weaning from mechanical ventilation is an essential and universal element in the care of mechanically ventilated patients. The weaning process comprises progressive withdrawal from the invasive ventilatory support until removal of the endotracheal tube and it could represent approximately 40% of the patient’s time on mechanical ventilation (MV). Tolerance of a spontaneous breathing test (SBT) mainly indicates the success of weaning, but variably predicts extubation success. After a successful SBT, the reported rate of cases who need reintubation within the subsequent 24 to 72 hours is high. The aim of this study is to evaluate the predictive value of central venous oxygen saturation (ScvO2), as a potential predictor of extubation failure in mechanically ventilated patients. This is a prospective cohort clinical study that included 50 patients admitted at respiratory intensive care unit in Abbassia chest hospital who were intubated and mechanically ventilated for a period of ≥48 hours and followed up for presence of post extubation respiratory distress for 48 hours.