SCLEROTHERAPY VERSUS BAND LIGATION OF ESOPHAGEAL VARICES: EFFECT ON HEPATIC AND RENAL FUNCTION

Abstract

Gastrointestinal bleeding driven by portal hype1iension represents a common and potentially life threatening complication of chronic liver disease. The most common and most serious site of bleeding is from gastroesophageal varices.

Endoscopic therapy 1s 'gold' standard for the treatment of acute variceal hemorrhage. There are currently two forms of endoscopic therapy that are widely used in this setting: - sclerotherapy and band ligation. The aim of the present study is to compare the effects of endoscopic injection sclerotherapy and endoscopic variceal ligation on hepatic and renal functions.

The present study was conducted on 90 patients with esophageal varices due to liver cirrhosis, their age ranged from I 8 - 65 years with mean (43.2 ± 9.56). They were 64 male and 26 female. They were admitted to tropical medicine department, Menoufiya University Hospital and classified into: -

Group I: - 30 patients with esophageal vances whom underwent elective endoscopic injection sclerotherapy (EIS Group). - Group II: - 30 patients with esophageal varices whom underwent elective endoscopic variceal ligation (EVL Group). - Group III: - 30 patients with esophageal varices whom underwent diagnostic upper GIT endoscopy (Control Group).