Value of Plasmatic Villin-1 in the prediction of early graft dysfunction in kidney transplant recipients among Egyptian population

Abstract

The study was conducted on seventy patients with end-stage renal disease with one or more risk factor for developing delayed graft function undergoing kidney transplantation from living donors attending the renal transplantation clinic at Ain shams University specialized Hospital (ASUSH), International medical center and Nile Badrawi specialized hospital in Egypt from May 2016 to July 2019 reviewed for eligibility criteria to be enrolled at our study which determined the sample size. These patients entered the run-in phase of the study and after exclusion of twenty-nine patients based on the exclusion criteria and developed of serious complications in the early post-operative period. Forty one patients were eligible and assigned into two groups according to the correlation with the serum creatinine levels in the first two days post transplantation after signed informed consent for participation in our study into group 1 (DGF group) where the patients developed DGF post-transplant (n=19) and group 2 (NGF group) where the patients didn't develop DGF post-transplant (n=22) To evaluate the diagnostic value of Plasmatic Villin-1 in the prediction of early graft dysfunction in kidney transplant recipients among Egyptian population.