Prevalence of HCV in patients with Relapsing Remitting Multiple sclerosis

Abstract

Multiple sclerosis (MS) is a complex immune mediated disorder of central nervous system. Multiple sclerosis is the most common non-traumatic cause of neurological disability in middle adulthood. There are four clinical phenotypes of MS. Initially, more than 80% of individuals with MS experience a relapsing-remitting disease course (RRMS) characterized by clinical exacerbations of neurologic symptoms followed by complete or incomplete remission. After 10 to 20 years, or median age of 39.1 years, about half of them gradually accumulate irreversible neurologic deficits with or without clinical relapses, which is known as secondary progressive MS (SPMS). Another 10% to 20% of individuals with MS are diagnosed with primary progressive MS (PPMS), clinically defined as a disease course without any clinical attacks or remission from onset.