Outcome of Critically Ill Patients with Acute Kidney Injury Requiring Sustained Low Efficiency Dialysis as Renal Replacement Therapy

Abstract

SUMMARY AND CONCLUSION Renal replacement therapy for the patients with acute renal failure in the intensive care unit can be offered in several different formats: intermittent hemodialysis (IHD), continuous renal replacement therapy (CRRT), and slow low efficiency daily dialysis (SLEDD). It is frequently claimed that CRRT offers several advantages over IHD, but most of these, such as correction of metabolic acidosis, better recovery of renal function, better clinical outcome due to application of biocompatible dialysis membranes, correction of malnutrition, and better removal of cytokines, are not corroborated by the results of prospective studies.