Retrospective Study of Managing Group A and B Retinoblastoma

Abstract

Retinoblastoma is the most common intraocular tumor in children. There are two forms heritable and non-heritable. Presentation is in the first few years of life, Leukocoria (white pupillary reflex or cat's eye reflex) is the most common presenting sign, accounting for about 56.1% of cases. Strabismus is the second most common mode of presentation. Other less common signs and symptoms of retinoblastoma include: Vision problems, Red painful eye with glaucoma, Hyphema, Bulging of the eye, Anisocoria, Heterochromia iridis, Orbital cellulitis & Nystagmus Thus, funduscopic examination through a well-dilated pupil must be performed in all cases of childhood strabismus. Early detection and prompt treatment can give cure rates up to 95% for intraocular tumors. The diagnosis is essentially clinical and biopsy is contraindicated due to the risk of extraocular spread. The primary goals of retinoblastoma treatment are to preserve the patient’s life and salvage the affected globe.