Thrombomodulin in Systemic Lupus Erythematosus and Juvenile Rheumatoid Arthritis
Arwa Fatfy Mohamed Fawzy;
Abstract
This study aimed at determining serum TM level in SLE
& JRA patients and studying its correlation with clinical and laboratory parameters to see if it could be a good serological marker of disease activity.
Patients included in this study were regularly attending the Allergy and Immunology Clinic, Children's Hospital, Ain Shams University. They were 38 (76%) females and 12 (24%) males, their ages ranged from 5 to 18 years with a mean age of (14.30±4.84 yrs). They were divided into two groups; group I; included 20 SLE patients and group II; inCluded 30 IRA patients. Group III; the control group included 30 healthy age and sex matched individuals for comparison.
All patients included in the study were subjected to :
Thorough history taking and clinical examination, disease activity scoring, laboratory investigations including: CBC, ESR; complete urine analysis, semm ANA, anti DNA & C3 (for SLE patients only); RF & CRP (for JRA patients).
The results of our study showed the following :
Semm TM levels were significantly higher in SLE patients and JRA patients in comparison to control group. There was no significant difference between SLE and JRA patients.
& JRA patients and studying its correlation with clinical and laboratory parameters to see if it could be a good serological marker of disease activity.
Patients included in this study were regularly attending the Allergy and Immunology Clinic, Children's Hospital, Ain Shams University. They were 38 (76%) females and 12 (24%) males, their ages ranged from 5 to 18 years with a mean age of (14.30±4.84 yrs). They were divided into two groups; group I; included 20 SLE patients and group II; inCluded 30 IRA patients. Group III; the control group included 30 healthy age and sex matched individuals for comparison.
All patients included in the study were subjected to :
Thorough history taking and clinical examination, disease activity scoring, laboratory investigations including: CBC, ESR; complete urine analysis, semm ANA, anti DNA & C3 (for SLE patients only); RF & CRP (for JRA patients).
The results of our study showed the following :
Semm TM levels were significantly higher in SLE patients and JRA patients in comparison to control group. There was no significant difference between SLE and JRA patients.
Other data
| Title | Thrombomodulin in Systemic Lupus Erythematosus and Juvenile Rheumatoid Arthritis | Other Titles | الثرومبوموديولين فى مرضى الذئبة الحمراء والروماتويد المفصلى الحدثى | Authors | Arwa Fatfy Mohamed Fawzy | Issue Date | 2001 |
Attached Files
| File | Size | Format | |
|---|---|---|---|
| B13827.pdf | 978.95 kB | Adobe PDF | View/Open |
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