Hypophosphatemia and weaning of Mechanically Ventilated patients with Chronic Obstructive Pulmonary Disease during acute exacerbations

Abstract

xacerbations of COPD are associated with high in-hospital and post-discharge mortality. Reported mortality rates vary from 2.5 to 30% depending upon patient characteristics and the design of the study. A recent investigation from the European Respiratory Society COPD audit that was designed as a prospective, observational, and non-interventional cohort trial found that 10.8% of those admitted with exacerbated COPD died during the observational period, from admission to 90 days after discharge. In expired patients, 45.7% died while still in hospital, whereas 54.3% died during the 90-day post-discharge follow-up.