Epicardial Fat Volume Assessed by Multi-Detector Computed Tomography and it’s Relation with the Severity of Coronary Artery Disease

Abstract

therosclerosis is a chronic inflammatory process with deposition of cholesterol in the wall of coronary arteries which leading to its stenosis and there is many factors leads to development of atherosclerosis as dyslipidemia and epicardial adipose tissue (EAT) which deposit around coronary arteries, causing ischemic heart disease. MSCT scan of the coronary arteries allows the evaluation of the degree of coronary stenosis, coronary plaque classification, coronary calcium scoring and epicardial fat volume estimation to help us in prediction of presence and severity of CAD. This study aimed to evaluate the relationship between epicardial fat volume and the severity of CAD among patients presented by chest pain with low to intermediate pretest probability for CAD by MSCT. The study was conducted on 40 patients, 30 males and 10 females with mean age 56 ± 10.27 years who were referred to the MSCT coronary angiography unit in Nasr City Police hospital during the period from August 2018 to April 2019. The patients underwent assessment of risk factors for atherosclerosis including (Age, sex, family history, diabetes mellitus, hypertension, smoking, dyslipidemia and BMI) and then referred for multi-slices CT coronary angiography to measure coronary calcium score (CAC), epicardial fat volume (EFV) and coronary plaque burden and stenosis by segment involvement score (SIS) and segment stenosis score (SSS) respectively.