Screening of Hip Osteonecrosis in Patients with Sickle Cell Disease and its Association with Hematological Parameters

Abstract

one involvement is the commonest clinical manifestation of sickle cell disease both in the acute setting such as painful vaso‐occlusive crises, and as a source of chronic, progressive disability such as avascular necrosis. Osteonecrosis of the femoral head in sickle cell disease has an insidious onset, and in the majority of patients progresses to femoral head collapse with rapid destruction of the hip joint. Early screening for femoral head AVN and identification of risk factors would help in placement of appropriate measures to prevent osteonecrosis in high risk patients. Our primary aim was to screen for femoral head osteonecrosis in sickle cell disease patients using conventional radiography and MRI for hip joints. As well as the association between MR findings with disease status and hematologic parameters.