Evaluation of Stem Cell Transplantation In Cerebral palsy

Abstract

CP is the most common motor disability in children with a prevalence of 2 per 1000 live births in developed countries. The prevalence of CP increases exponentially in preterm infants with decreasing gestational age. For example, the risk to develop CP is 30 times higher in infants born before 33 weeks gestation compared to term-born infants. Besides prematurity, major risk factors include placental abnormalities, major and minor birth defects, low birth weight, meconium aspiration, emergency caesarean section, birth asphyxia, neonatal seizures, respiratory distress syndrome, hypoglycemia, and neonatal infections The aim of the study is to evaluate the role of stem cells transplantation in CP Patients This is a follow up study, that was carried out at waady Elneel hospital, Cairo, the study was conducted on 20 diagnosed Cerebral Palsy patients classified according to Age into Two Groups: Group 1: one year to five years, and Group 2: five years to fifteen years, the study was carried out from January 2018 to January 2020, Follow up the patient with convulsions was done before injection of stem cell and 3 months, 6 months, 9 months, 12 months after injection of stem cell. The results of the study revealed that:  Mean age in total of CP cases is 6.7±3.98 with range of (1.5-14), mean age of maternal is 34.7±7.7 with range of (19-44). 45% OF Cases were males and 55% were females.